Does high dose intravenous acetaminophen affect liver function for PDA closure in premature neonate?

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Efficacy and complications of oral ibuprofen and intravenous acetaminophen in closure of patent ductus arteriosus of preterm neonates

Background: Previous studies have considered patent ductus arteriosus (PDA) a common finding in premature infants, leading to complications such as intracranial hemorrhage, necrotizing enterocolitis and pulmonary dysplasia. The aim of this study was to assess and compare the efficacy of oral ibuprofen and intravenous acetaminophen in the closure of arterial duct in premature newborns. We also e...

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ژورنال

عنوان ژورنال: Italian Journal of Pediatrics

سال: 2021

ISSN: 1824-7288

DOI: 10.1186/s13052-020-00940-2